Investigation of Morinda citrifolia Activity Related Collagen Type II Synthesis Through Gene Expression

To extend plant benefits, three different concentrations of five Morinda citrifolia part was investigated on the collagen type II which is primary in human cartilage through expression genes, COL2A1, COL-II and COLL2 regions normal dermal fibroblasts by qRT-PCR method. The results showed that 1) cultured presence M. extracts produced many times more gene than control cells depending parts concentrations, 2) levels stimulated all fruit yields higher percentages leaves. Next, Morus alba leaf extract at a concentration expected to be precursor protein source for synthesis, working together with stimulation, added selected indicating high experiments. result various depended kind part. Therefore, fruits can benefit creation or without alba. further benefited product production both elderly young maintaining typical structure function skin, tendon, bone.